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Target intelligence / Profile preview
Clathrin-binding box of aftiphilin-containing protein 1 (CLBA1)
- Target
- CLBA1
- Molecular classification
- Other (uncharacterized protein), Predicted member of aftiphilin-like protein family[7]
01
Overview
Clathrin-binding box of aftiphilin-containing protein 1 (CLBA1) is a protein encoded by the *CLBA1* gene on human chromosome 14. It is predicted to play a role in intracellular transport through **clathrin binding** and to function as part of the **AP-1 adaptor complex**, mainly active at the **trans-Golgi network membrane**. The protein remains functionally uncharacterized, with no experimental evidence establishing its role in disease, therapeutics, or as a drug target[1][3][5][9][11]. Its classification as a member of the aftiphilin-like family is based on sequence similarity[7], and no known ligands, biomarkers, or clinical implications have been described.
- Other names
- C14orf79Uncharacterized protein CLBA1Clathrin binding box of aftiphilin containing 1Clathrin-binding box of aftiphilin-containing protein 1
02
Mechanism of action
Not applicable
03
Biological functions
Predicted clathrin binding activity[1][3][5]Predicted involvement in intracellular transport[1][3]Predicted association with AP-1 adaptor complex[1][3]Predicted to be active at the trans-Golgi network membrane[3][5][11]
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