Clavibacter michiganensis (C. michiganensis)

Clavibacter michiganensis is a Gram-positive, aerobic bacterium and a major plant pathogen primarily responsible for bacterial canker in tomatoes (Source: American Phytopathological Society). It is characterized by its ability to colonize the plant's vascular system, specifically the xylem, leading to systemic symptoms such as wilting, leaf necrosis, and fruit spotting (Source: Wikipedia). As an entire organism, it is not classified as a specific molecular therapeutic target like a receptor or enzyme, but rather as the causative agent of disease. Management of this pathogen typically involves agricultural bactericides, including copper-based compounds and antibiotics like streptomycin, which inhibit bacterial growth and protein synthesis (Source: PubMed). Research into its virulence highlights the role of plasmid-encoded factors, such as the cellulase CelA and the serine protease Pat-1, which are essential for host colonization and tissue degradation (Source: Journal of Bacteriology). Because it is a complex biological entity rather than a single molecule, it is considered an incorrect entry for a specific molecular target database.

Other names

Corynebacterium michiganenseMycobacterium michiganenseBacterial canker of tomato

Inhibition of bacterial protein synthesis via the 30S ribosomal subunit (aminoglycosides/tetracyclines) or induction of oxidative stress and membrane damage (copper-based bactericides).