CLRN1 and FAM188B2 readthrough transcript

CLRN1 and FAM188B2 readthrough transcript (ENSG00000260234) refers to a naturally occurring fusion transcript that spans two adjacent genes: CLRN1, which encodes clarin-1 (a four-transmembrane protein crucial for neurosensory function in the inner ear and retina), and FAM188B2, whose function is poorly characterized. The readthrough is annotated based on transcriptional sequencing evidence but has no validated protein function, pathological association, or established therapeutic targeting relevance. Current disease links, biological functions, and molecular detail are all attributed to the canonical CLRN1 gene—not the readthrough form. This entity is not considered a receptor, enzyme, transporter, or transcription factor, and its therapeutic significance is unreported in the literature.

Other names

CLRN1-FAM188B2 readthroughCLRN1 and FAM188B2 read-through transcript