CMC1 pseudogene 2 (CMC1P2)

CMC1 pseudogene 2 (CMC1P2) is a non-coding genetic element similar in sequence to the functional CMC1 gene, which encodes a mitochondrial protein that participates in the early steps of cytochrome c oxidase complex assembly[1][2][3]. However, as a pseudogene, CMC1P2 does not produce a functional protein and has no known biological or therapeutic relevance, nor any established role in disease or drug interaction. The true functional protein, CMC1, is a mitochondrial intermembrane space protein critical for COX complex stability and assembly, but CMC1P2 itself does not share these functions. Key clarification: CMC1P2 is not a therapeutic target; it is a pseudogene (a genomic "copy" that is not translated into a functional protein). There may be confusion in databases or literature due to similarity in names with the functional CMC1 gene/protein, but only CMC1 (not CMC1P2) is functionally involved in COX assembly and potentially mitochondrial diseases[1][2][3]. If you are seeking information on the functional protein involved in COX assembly, refer instead to COX assembly mitochondrial protein 1 (CMC1) and not its pseudogenes.

Other names

COX assembly mitochondrial protein homolog, CMC1P2CMC1P2