Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Coagulation Factor IX (FIX) (FIX)
- Target
- FIX
- Molecular classification
- Enzyme, Other
01
Overview
- Other names
- Christmas factorPlasma thromboplastin componentPTCF9Coagulation factor 9Coagulation Factor IX-dependent hemostatic cascade
02
Mechanism of action
Replacement of the deficient clotting factor to restore the intrinsic tenase complex activity, gene-based delivery for endogenous protein production, or direct inhibition of the activated protease to prevent thrombin generation [4, 5, 13].
03
Biological functions
Other
04
Disease associations
Cardiovascular diseaseOther
05
Safety considerations
Development of neutralizing antibodies (inhibitors) [13]Thromboembolic events [1, 13]Hypersensitivity and anaphylactic reactions [13]Nephrotic syndrome [13]Infusion}
06
Interacting drugs
Nonacog alfa
7 more in the full profile.
07
Biomarkers
Factor IX activity (FIX:C) [6]Activated partial thromboplastin time (aPTT) [5, 13]Factor IX antigen levels [13]Factor IX inhibitor titers [13]
Beyond the preview
Go deeper on Coagulation Factor IX (FIX) (FIX).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Coagulation Factor IX (FIX) (FIX).