Coiled-coil and C2 domain containing 2B (CC2D2B)

Coiled-coil and C2 domain containing 2B (CC2D2B) is a protein predicted to participate in the assembly and maintenance of the non-motile cilium, specifically contributing to the architecture and function of the ciliary transition zone[1][4]. It contains a transglutaminase-like domain, potentially mediating cilia-specific peptidase activity or protein–protein interactions important for ciliogenesis[1]. CC2D2B is not currently regarded as a direct therapeutic target such as a receptor, enzyme, transporter, or channel, and there are no known drugs or mechanisms of action directly associated with this molecule. It is listed as a protein-coding gene, with roles in cellular architecture rather than canonical signaling or disease pathways. While CC2D2B has been implicated in disease biomarker studies, it is not definitively linked to specific pathologies, in contrast to its more closely studied paralog CC2D2A[4]. Key points: - CC2D2B is a structural and regulatory protein involved in cilium biology, without direct evidence of drug targeting, biomarker use, or therapeutic relevance as of current literature[1][4]. - Alternative names and prior symbols encompass C10orf130, C10orf131, and related locus numbers[1][4]. - No known safety concerns or drug interactions have been reported for CC2D2B to date. Limitations: No evidence supports its function as a receptor or direct therapeutic target; its roles are currently limited to cellular and structural biology references, with nominal associations in biomarker studies[1][4].

Other names

C10orf130C10orf131BA248J23.4bA248J23.4bA690P14.3protein CC2D2Buncharacterized protein C10orf131C2D2B_HUMAN