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Coiled-coil domain containing 112 pseudogene (LOC100132834, ENSG00000276127) is a human genomic locus annotated as a pseudogene—DNA resembling a protein-coding gene but rendered nonfunctional by disabling mutations.[1][2][5] Pseudogenes typically do not encode functional proteins and are generally excluded as direct therapeutic targets or receptors.[2] They may sometimes be transcribed as noncoding RNA and can potentially influence gene regulation, including through microRNA decoy activity, but there is currently no evidence that this specific pseudogene has known biological functions or implications in human disease.[1][4] Key context and clarification: - This locus is not a protein-coding gene, nor is it a receptor, enzyme, or other classical drug target. - Pseudogenes like this occasionally acquire regulatory RNA functions, but that is not established for this gene specifically.[4][6] - There is no indication of interacting drugs, therapeutic relevance, or biomarker status. - The gene is better classified as a genomic annotation with no current evidence for direct biomedical or therapeutic utility.
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