Coiled-coil domain containing 144 N-terminal like pseudogene (ENSG00000275480)

Coiled-coil domain containing 144 N-terminal like pseudogene (ENSG00000275480) is annotated in the human genome as a pseudogene, meaning it is a segment of DNA that resembles a functional gene but is not capable of producing a functional protein. Pseudogenes arise from gene duplication or retrotransposition events and accumulate mutations over time, resulting in loss of function. Most pseudogenes have no biological activity, though rare examples may exert regulatory effects in cis or trans, but this has not been demonstrated for ENSG00000275480 or directly related pseudogenes. The coiled-coil domain containing 144 family includes CCDC144A, CCDC144B, CCDC144C, and putative N-terminal like pseudogenes. While some members encode proteins with potential functional roles, the N-terminal like variant is annotated as a pseudogene, with insufficient evidence for protein expression or activity and no reported involvement in disease or clinical application. In summary, ENSG00000275480 represents a nonfunctional pseudogene with no current relevance for drug targeting or biomarker use in human biology or medicine.

Other names

CCDC144NLCoiled-coil domain containing 144 N-terminal like pseudogenePutative coiled-coil domain-containing protein 144 N-terminal-like pseudogene

None. As there are no known drugs targeting this pseudogene, there are no mechanisms of action described.