Coiled-coil domain containing 58 pseudogene (CCDC58P)

Coiled-coil domain containing 58 pseudogene (CCDC58P) is a human genomic locus classified as a pseudogene, which resembles the coiled-coil domain containing 58 gene but is not translated into a functional protein and is not reported to have a known biological or therapeutic function[4][6][7]. Pseudogenes are commonly considered non-functional remnants of genes and do not act as receptors, enzymes, or therapeutic targets[7]. In contrast, the protein-coding gene *Coiled-coil domain containing 58* (CCDC58) is an active gene involved in mitochondrial import machinery and tumor biology, but the pseudogene with the ENSG00000270251 identifier lacks evidence of function or clinical significance[7][5]. Key context for data curation and identifier accuracy: - ENSG00000270251 denotes a **pseudogene** corresponding to CCDC58, not the active CCDC58 protein[7]. - There is confusion in literature between CCDC58 (protein-coding, possible biomarker in cancer) and its pseudogenes, but **only the protein-coding CCDC58 is studied as a biomarker or target**[5][9]. - Pseudogenes are not generally pursued as drug targets, biomarkers, or therapeutic receptors. - No drugs, mechanisms of action, disease associations, or safety concerns are established for CCDC58 pseudogene[7]. If you are seeking **therapeutically relevant information**, consult entries for the active gene **coiled-coil domain containing 58 (CCDC58)**, *not* the pseudogene with this Ensembl ID[5][9].

Other names

CCDC58PCCDC58P1Coiled-coil domain containing 58 (pseudogene)[CCDC58 pseudogene]