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Coiled-coil domain containing 90B pseudogene (CCDC90B pseudogene)
- Target
- CCDC90B pseudogene
- Molecular classification
- Pseudogene, Other
01
Overview
Coiled-coil domain containing 90B pseudogene (LOC643014, ENSG00000251017) is a genomic element classified as a pseudogene, meaning it resembles the functional CCDC90B coding gene but has accumulated mutations that prevent it from encoding a functional protein[1][4][5][7][10]. Pseudogenes may be transcribed as RNA and can participate in regulatory processes, such as acting as microRNA decoys or producing interfering RNAs that affect gene expression; however, specific biological roles for this particular pseudogene are uncharacterized. While some pseudogenes have emergent regulatory functions or serve as noncoding RNA sources, the LOC643014 locus is *not* recognized as a therapeutic target, marker, or established participant in disease[2][10].
- Other names
- LOC643014CCDC90B pseudogeneCoiled-coil domain containing 90B pseudogene
02
Biological functions
May be transcribed and play roles in regulating expression of coding genes via RNA interference pathways, as microRNA decoys, or through competition for regulation factors, as documented for certain pseudogenes. However, direct biological functions for this specific pseudogene (LOC643014) are uncharacterized.
03
Disease associations
Other. Per general literature, some pseudogenes can regulate genes involved in cancer and other diseases. There is no evidence that LOC643014 itself plays an established role in specific diseases.
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