Coiled-coil domain-containing protein 140 long non-coding RNA (CCDC140 lncRNA)

CCDC140 long non-coding RNA (CCDC140 lncRNA) is a transcript classified as a long non-coding RNA (lncRNA), typically defined as RNA molecules longer than 200 nucleotides that do not encode proteins[4][5][6]. The CCDC140 gene is mostly noted for its lncRNA form and shows limited expression in select higher primates[4]. LncRNAs perform various roles including the regulation of gene expression, chromatin organization, scaffolding of protein complexes, and modification of epigenetic states[1][2][3][5]. CCDC140 lncRNA is affiliated with epigenetic regulation and gene expression, and diseases associated with CCDC140 include Waardenburg syndrome type 1 and brain meningioma, suggesting roles in development and potentially in oncogenesis[4]. There is no evidence to indicate that CCDC140 lncRNA encodes a functional receptor, enzyme, or other established therapeutic target class[4][5][6]. No drugs are currently known to selectively target this lncRNA, and it is not considered a conventional therapeutic target. There is also limited disease biomarker data, and detailed safety concerns for therapeutic targeting are not known. CCDC140 lncRNA is a long non-coding RNA, not a receptor or classic drug target molecule. It is involved in regulation of gene expression and possibly chromatin organization but lacks established drug interactions[4][5]. It has associations with certain diseases but no established mechanisms of drug action or usage as a clinical biomarker. Its main scientific value is in basic research rather than as a therapeutic target at this time.

Other names

CCDC140FLJ32447Coiled-coil domain-containing protein 140CCDC140 long non-coding RNAcoiled-coil domain containing 140