Coiled-coil domain-containing protein 148 (CCDC148)

Coiled-coil domain-containing protein 148 (CCDC148) is a protein-coding gene in humans located on chromosome 2[2][5][3]. Its precise biological function is not well characterized, but available evidence suggests it is involved in protein binding, and its sequence contains a coiled-coil structural domain[8][9][5]. No direct evidence links CCDC148 to established signaling pathways, well-defined molecular complexes, or typical drug-target classes such as receptors, enzymes, transporters, or transcription factors[2][5][8][3]. There are no known pharmacological agents or disease biomarkers directly acting upon or through CCDC148, and it is not currently considered a validated therapeutic target. Some associations have been noted with diseases such as tyrosinemia type II and benign epilepsy with centrotemporal spikes; however, the mechanistic or causal relationship remains unclear[2]. This protein is also referred to as "coiled-coil domain containing 148" and "coiled-coil domain-containing protein 148," with CCDC148 being the gene and protein symbol most commonly used in the literature[3][9][2]. Currently, there are limited experimental data addressing its molecular or cellular role, disease mechanisms, or therapeutic potential.

Other names

coiled-coil domain containing 148CCDC148coiled-coil domain-containing protein 148