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Coiled-coil domain-containing protein 24 (CCDC24)

Target: CCDC24
Molecular classification: Other (specifically, protein containing a coiled-coil domain; not a member of classical drug target families like receptors, enzymes, ion channels, transporters, or transcription factors)

Overview

Coiled-coil domain-containing protein 24 (CCDC24) is a human protein encoded by the CCDC24 gene. The defining feature is the presence of a coiled-coil domain, a structural motif that facilitates protein-protein interactions and serves as a molecular spacer in various cellular contexts. While the exact biological function of CCDC24 is not well-characterized, prediction-based annotation suggests a possible role upstream of blastocyst hatching. Diseases associated with CCDC24 include juvenile glaucoma, but its involvement in broader disease mechanisms—such as cancer—is only suggested by extrapolation from the larger coiled-coil domain-containing protein family, not by direct evidence for CCDC24 itself. To date, CCDC24 is not considered a classical therapeutic target, and there are no drugs or biomarker usages documented for this specific protein.

Other names: CCDC24Coiled-coil domain containing 24MGC45441CCD24

Biological functions

Molecular spacing (likely as a structural component due to coiled-coil domain)May act upstream of blastocyst hatching (predicted function)As with other CCDC proteins: possible roles in gametogenesis, embryonic development, hematopoiesis, angiogenesis, ciliary development (inferred by homology, not directly shown for CCDC24)

Disease associations

Juvenile glaucoma (disease association in humans)Potential cancer involvement (CCDC proteins as a family have known cancer roles, but no direct strong evidence specifically for CCDC24)

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