Target intelligence / Profile preview

Coiled-coil domain-containing protein R3HCC1L (R3HCC1L)

Target
R3HCC1L
Molecular classification
Other
01

Overview

Coiled-coil domain-containing protein R3HCC1L (R3HCC1L) is a protein-coding gene located on human chromosome 10, encoding a protein with an R3H domain and coiled-coil motifs. It is ubiquitously expressed, with particularly high abundance in testis and is present in both the nucleus and cytoplasm in most tissues[4]. Its annotated molecular function involves nucleotide binding[1]. Diseases associated with the gene include Far Eastern Spotted Fever and certain congenital brain and renal developmental disorders[1][5]. It has not been widely studied as a direct therapeutic target, and there are no known drugs or mechanisms of action involving this protein[1][5][7].

Other names
C10orf28GIDRP88PSORTGrowth inhibition and differentiation-related protein 88Putative mitochondrial space protein 32.1R3H and coiled-coil domain-containing protein 1-likeGIDRP86
02

Biological functions

Nucleotide binding
03

Disease associations

Far Eastern Spotted FeverMultinucleated NeuronsAnhydramniosRenal DysplasiaCerebellar HypoplasiaHydranencephaly

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