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Target intelligence / Profile preview
Coiled-coil serine-rich protein 1 (CCSER1)
- Target
- CCSER1
- Molecular classification
- Other (structural/regulatory protein)
01
Overview
Coiled-coil serine-rich protein 1 (CCSER1) is essential for mitosis and cytokinesis, frequently altered in cancer, and implicated in cellular proliferation, chromosomal stability, and as a source of tumor neo-antigens. No direct drugs exist; a potential future biomarker and therapeutic target in oncology[1][3].
- Other names
- FAM190AKIAA1680Serine-rich coiled-coil domain-containing protein 1Family with sequence similarity 190 member AProtein FAM190ACCSER1
02
Mechanism of action
Not established for direct targeting.
03
Biological functions
Cell cycleCytokinesisCell proliferationMaintenance of genomic stability
04
Disease associations
CancerCocaine dependenceAlcohol dependenceHypomyelinating leukoencephalopathy
05
Safety considerations
Disruption of normal cell divisionpotential cytopeniaschromosomal instability
06
Biomarkers
CCSER1 rearrangementsCCSER1 deletionsTumor-specific neo-antigens
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