Collagen type XI alpha 2 pseudogene 1 (COL11A2P1)

Collagen type XI alpha 2 pseudogene 1 (COL11A2P1) is a genomic DNA sequence with homology to the gene encoding the alpha-2 chain of type XI collagen (COL11A2), but it is a pseudogene, meaning it does not code for a functional protein and is not expressed as a receptor, enzyme, or structural component[5]. The functional gene *COL11A2* (collagen type XI alpha 2 chain) is responsible for encoding a minor fibrillar collagen crucial for cartilage and connective tissue integrity and, when mutated, is linked to conditions such as Stickler syndrome, otospondylomegaepiphyseal dysplasia, and hearing loss[1][2][3][4]. However, COL11A2P1 itself is not functional, not associated with therapeutic targeting, and not implicated in disease biology or pharmacology[5]. Its only relevance is as a genomic locus used in research to clarify the context or annotation of the functional *COL11A2* gene. Key points regarding inaccuracy or confusion: - COL11A2P1 is sometimes confused with *COL11A2*, the active gene coding for a collagen alpha chain crucial in connective tissue[1][2][3][4]. - COL11A2P1 is a pseudogene—by definition, not a molecular target. There are no drugs or mechanisms associated with this locus, nor disease links, nor molecular function or classification as receptor, enzyme, or other actionable protein[5]. If you were seeking a molecular target with real biological or pharmacological significance, you likely intended *Collagen type XI alpha 2 chain* (*COL11A2*), not the pseudogene *COL11A2P1*.

Other names

cD0826Q1.1COL11A2Pcollagen, type XI, alpha 2 pseudogene

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