Target intelligence / Profile preview

Collagen type XXVI alpha 1 chain (COL26A1)

Target
COL26A1
Molecular classification
Collagen family, Structural extracellular matrix protein
01

Overview

Collagen type XXVI alpha 1 chain is a fibrillar collagen component belonging to the collagen superfamily of extracellular matrix (ECM) structural proteins. It is encoded by the COL26A1 gene and forms homotrimers that contribute to tissue structural integrity. Expression studies in mouse development demonstrate localization in somites, mesenchymal tissues of the head, and branchial arches during embryogenesis, suggesting a role in early tissue organization. Unlike many other collagen types, type XXVI has not been directly linked to common connective tissue disorders, nor is it recognized as a therapeutic target for drugs or disease biomarker in current biomedical literature.

Other names
Collagen alpha-1(XXVI) chainCOL26A1
02

Biological functions

Extracellular matrix organizationCellular structural supportDevelopmental tissue morphogenesis
03

Disease associations

Other (no direct association with major human diseases such as cancer, inflammation, or neurodegenerative disease found in available databases or literature)

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