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Target intelligence / Profile preview
Colonization Factor Antigen 3 (CS3)
- Target
- CS3
- Molecular classification
- Fimbrial protein, Adhesin
01
Overview
CS3 is a fimbrial colonization factor antigen (CFA) expressed by certain strains of enterotoxigenic Escherichia coli (ETEC). It mediates bacterial adhesion to intestinal cells, facilitating colonization and contributing to diarrheal disease. CS3 consists of thin, flexible fimbriae and is immunogenic, eliciting an antibody response during infection. It is a target for diagnostics and vaccine development against ETEC.
02
Mechanism of action
Adherence to intestinal epithelial cells
03
Biological functions
Bacterial adhesionColonizationVirulence
04
Disease associations
Enterotoxigenic Escherichia coli (ETEC) infectionDiarrheal disease
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