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Colorectal cancer cells comprise the heterogeneous population of cells that make up tumors arising in the colon or rectum. These cells display a range of genetic, epigenetic, and phenotypic alterations—including common mutations in genes such as APC, KRAS, TP53, and PIK3CA—that drive malignancy, metastasis, and therapeutic resistance. Molecular and pathological characterization of these cells is critical for diagnosis, prognosis, and the development of targeted therapies. However, 'colorectal cancer cells' is not a specific molecular entity, and clinical interventions are usually directed at discrete molecular components or pathways within these cells rather than the population itself.
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