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Target intelligence / Profile preview
Complement factor H-related family member pseudogene (CFHR pseudogene)
- Target
- CFHR pseudogene
- Molecular classification
- Other (Pseudogene)
01
Overview
The "complement factor H-related family member pseudogene CFHR" is a pseudogene, meaning it is a nonfunctional DNA sequence similar in structure to the family of complement factor H-related (CFHR) genes. Pseudogenes typically arise from duplication or mutation of functional genes and lose the ability to encode a functional protein product[4]. While some pseudogenes may have regulatory RNA roles or produce non-functional peptides, the CFHR pseudogene is not known to have direct biological or clinical significance, nor is it an established drug target[2][3][4]. The functional CFHR1-5 genes, but not the pseudogenes, are implicated in renal and complement disorders when altered, especially through hybrid gene formation with CFH[1].
- Other names
- CFHR pseudogenecomplement factor H-related pseudogenepotential database-origin systematic names
02
Biological functions
Other (May have regulatory or competing RNA functions in some contexts, but does not encode a functional protein)
03
Disease associations
Other (CFHR pseudogene itself does not have established disease roles; however, recombination between CFH and CFHR1 genes—distinct from the pseudogene—can be implicated in atypical hemolytic uremic syndrome)
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