Complement System Protein Inhibitor (None)

Complement system protein inhibitors are molecules that regulate or block the activation of the complement system, a crucial part of innate immunity. They act at multiple points in the complement cascade to prevent excessive or inappropriate activation, protecting host tissues from damage. These inhibitors can be endogenous proteins or therapeutic agents, including monoclonal antibodies and small molecules. They are used to treat diseases where complement overactivation contributes to pathology, such as autoimmune disorders, blood disorders, and hereditary angioedema.

Binds and inactivates specific complement proteins or receptors, preventing their activation or downstream signaling.