Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Contactin-associated protein family member 3 (CNTNAP3)
- Target
- CNTNAP3
- Molecular classification
- Other (cell-recognition molecule, neurexin superfamily)
01
Overview
Contactin-associated protein family member 3 (CNTNAP3, also known as CASPR3) is a neuron-glia cell adhesion molecule belonging to the neurexin superfamily. It plays a role in cell recognition within the nervous system, axon myelination, neural network formation, and maintaining the stability of neuronal connections. Loss-of-function and rare missense mutations in CNTNAP3 have been linked to neurodevelopmental disorders such as autism spectrum disorder, and abnormal expression has been associated with schizophrenia. The biological significance of its various isoforms, generated via alternative splicing, is not fully understood, and no drugs are currently known to target CNTNAP3 directly[1][2][3][6].
- Other names
- Contactin-associated protein-like 3CASPR3KIAA1714CNTNAP3AFLJ14195cell recognition molecule Caspr3contactin associated protein like 3RP11-204I2.1RP11-138L21.1RP11-290L7.1
02
Biological functions
Cell recognition within the nervous systemNeuron-glial interactionAxon myelinationNeural network formation
03
Disease associations
Neurodevelopmental disorders (including autism spectrum disorder, Asperger syndrome)SchizophreniaPotential roles in neurodegenerative disease, multiple sclerosis, and autoimmune encephalitis
Beyond the preview
Go deeper on Contactin-associated protein family member 3 (CNTNAP3).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Contactin-associated protein family member 3 (CNTNAP3).