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COP9 signalosome subunit 5 pseudogene 2 (COPS5P2) is a pseudogene, which means it is a DNA sequence similar to a known gene (COPS5/COP9 signalosome subunit 5) but is generally considered non-functional and does not produce a functional protein product[1][4]. Unlike protein-coding genes that serve as drug targets, pseudogenes like COPS5P2 lack established protein expression, biological functions, or direct clinical relevance. If the intention is to refer to a therapeutic target or a biologically active protein, the correct entry would be "COP9 signalosome subunit 5" (COPS5 or CSN5), not the pseudogene COPS5P2[1][4]. Key point: COPS5P2 refers specifically to a pseudogene, not to the functional subunit 5 of the COP9 signalosome complex, and is not considered a therapeutic target[1][4]. For information on the biologically active form, refer to COP9 signalosome subunit 5 (COPS5/CSN5), which is a protein involved in protein degradation, signaling, and cell cycle regulation, and has disease relevance[2][3][5][7].
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