Copper and zinc ions (Cu/Zn)

Copper and zinc ions are essential trace elements that function as vital cofactors for a wide array of enzymes and structural proteins in the human body. Copper is integral to cellular respiration, iron oxidation, and pigment formation, while zinc is crucial for over 300 enzymatic reactions, including those involved in DNA synthesis and immune response. Pathological imbalances in these ions are associated with genetic disorders such as Wilson's disease and Menkes disease, as well as chronic conditions like neurodegeneration and cardiovascular disease. Pharmacological strategies targeting these ions primarily involve chelation therapy to reduce toxic accumulation or supplementation to address deficiencies. Furthermore, research into metal-protein interactions continues to explore how modulating these ions can impact the progression of diseases like Alzheimer's, where copper and zinc are thought to contribute to protein aggregation.

Other names

Copper(II) ionsZinc(II) ionsCu2+Zn2+Cupric ionsZinc ions

Chelation of metal ions to facilitate urinary excretion; competitive inhibition of intestinal absorption; restoration of metal homeostasis in the central nervous system.