Corneal tissue

The corneal tissue consists of five main layers: the *epithelium* (regenerative protective surface), *Bowman's layer* (collagenous acellular barrier), *stroma* (collagen-rich connective tissue for transparency and strength), *Descemet's membrane* (basement membrane for endothelium), and *endothelium* (monolayer regulating hydration)[5][6]. The stroma comprises mainly type I and V collagen fibrils, organized to minimize light scattering, interspersed with keratocytes and small leucine-rich proteoglycans (lumican, decorin, keratocan, biglycan)[1][2][3][4]. Its primary biological role is maintaining vision by providing a transparent, strong, and smooth surface for light entry. As a tissue or organ, "corneal tissue" cannot be considered a precise molecular therapeutic target; rather, its individual molecular components (e.g., collagen, proteoglycans, ion channels) may serve as therapeutic, diagnostic, or research targets.

Other names

CorneaCorneal stroma (when referring to its main layer)Corneal epithelium (for its outer layer)

Not specific to a molecule; actions depend on drug class Antibiotics: inhibit bacterial growth at the corneal surface Corticosteroids: reduce inflammatory cytokine production Immunomodulators: suppress T-cell mediated inflammation