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Target intelligence / Profile preview
Coronary Artery
- Molecular classification
- Blood vessel, Artery
01
Overview
The coronary arteries are the primary blood vessels responsible for supplying oxygen-rich blood to the heart muscle (myocardium). They originate from the aortic root and include the Left Main Coronary Artery (LMCA), which branches into the Left Anterior Descending (LAD) and Left Circumflex arteries, and the Right Coronary Artery (RCA). Their main function is delivering oxygenated blood directly to cardiac muscle cells. Pathologies like atherosclerosis can lead to coronary artery disease, resulting in angina, myocardial infarction, or arrhythmias.
02
Mechanism of action
Not applicable - drugs target the underlying disease processes (e.g., atherosclerosis) or manage symptoms (e.g., angina).
03
Biological functions
Oxygen transportNutrient deliveryMyocardial perfusion
04
Disease associations
Coronary Artery DiseaseMyocardial InfarctionAnginaAtherosclerosisIschemic Heart Disease
05
Safety considerations
Vascular injury during interventions (e.g., angioplasty)Restenosis after angioplasty/stentingBleeding complications with antiplatelet therapy
06
Interacting drugs
Statins
4 more in the full profile.
07
Biomarkers
Troponin (for myocardial infarction)LDL cholesterol (for atherosclerosis risk)CRP (C-reactive protein, for inflammation)
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