COX17 pseudogene 1 (COX17P1)

COX17 pseudogene 1 (COX17P1) is a non-functional genetic element located on chromosome 13, sharing sequence similarity with the functional COX17 gene, which encodes a mitochondrial copper chaperone[2][1]. The pseudogene is characterized by nucleotide changes—including alterations in the copper binding domain—that prevent it from producing active protein. Pseudogenes such as COX17P1 have no known roles in copper trafficking, mitochondrial function, or disease, and are not considered therapeutic targets. Only the functional COX17 gene has established involvement in mitochondrial copper transport and assembly of complex IV of the respiratory chain, but COX17P1 itself is genomically silent and not biologically relevant as a drug target[2][1][5].

Other names

COX17PCOX17P1 pseudogene