Target intelligence / Profile preview

Coxsackie virus and adenovirus receptor pseudogene 1 (CXADRP1)

Target
CXADRP1
Molecular classification
Other (Pseudogene)
01

Overview

CXADRP1 (Coxsackie virus and adenovirus receptor pseudogene 1) is a human pseudogene found on chromosome 21 at location 21q11.2, according to HUGO Gene Nomenclature Committee and Monarch Initiative resources[4][7]. Pseudogenes are genomic DNA sequences similar to normal genes but non-functional; they typically arise from duplication or retrotransposition events[2][4][5]. CXADRP1 shares homology with the CXADR gene, which encodes the Coxsackievirus and adenovirus receptor (CAR), but CXADRP1 itself does not encode a functional protein or possess receptor activity[2][4][7]. It does not participate in cell adhesion, virus binding, or intracellular signaling. There is currently no evidence for a therapeutic or biomarker role for this pseudogene. Key clarification: References to functional activity ("CAR", "receptor") pertain to CXADR, not CXADRP1. This entry is not a therapeutic target or functional receptor. If protein or therapeutic target information is required, see CXADR, not CXADRP1[1][3][7].

Other names
CARCXADRPcoxsackie virus and adenovirus receptor pseudogene 1

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