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Target intelligence / Profile preview
CPB2 antisense RNA 1 (CPB2-AS1)
- Target
- CPB2-AS1
- Molecular classification
- Long non-coding RNA, Antisense RNA, Non-protein coding RNA
01
Overview
CPB2 antisense RNA 1 (CPB2-AS1) is a long non-coding RNA that is transcribed from the strand opposite the CPB2 gene and acts as a negative regulator of CPB2 expression in hepatocytes, serving to fine-tune basal production of CPB2. Like other antisense RNAs, it may modulate gene expression through epigenetic, transcriptional, and post-transcriptional mechanisms, but no direct role in disease or as a drug target has been established. CPB2-AS1 is annotated in human databases as a non-protein coding RNA with sequence complementarity and regulatory roles relevant to its sense gene, CPB2.
- Other names
- CPB2-AS1CPB2 antisense RNA 1 (non-protein coding)
02
Biological functions
Negative regulation of CPB2 gene expression (in hepatocytes)Epigenetic and transcriptional modulationFine-tuning basal gene expression levelsPotential involvement in RNA stability and chromatin modifications, as seen broadly for antisense RNAs
03
Disease associations
Other (no direct roles in specific diseases reported for CPB2-AS1; generally, antisense RNAs may be involved in cancer, neurological disease, and other disorders, but no evidence for CPB2-AS1 itself)
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