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Crab Protein Allergen

Molecular classification: Protein, Allergen

Overview

Crab protein allergens are proteins found in crab meat that can trigger allergic reactions. The primary allergen is tropomyosin, exhibiting high cross-reactivity with other crustaceans, mollusks, mites, and cockroaches. Arginine kinase is another identified allergen. Exposure can cause hives, itching, swelling, GI distress, respiratory issues, and potentially life-threatening anaphylaxis. Occupational exposure is a risk for processing plant and vessel workers.

Other names: Crab allergenCrab meat allergenTropomyosin (crab)Arginine kinase (crab)

Biological functions

Elicitation of allergic immune responseAntigen presentationIgE binding

Disease associations

Food allergyOccupational asthmaAnaphylaxis

Safety considerations

AnaphylaxisCross-reactivity with other shellfish and arthropodsOccupational exposure leading to asthma

Biomarkers

IgE antibodies against crab proteinsSkin prick test positivity

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