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CREB-binding Protein Bromodomain
- Molecular classification
- Bromodomain, Epigenetic regulator, Histone modification reader
01
Overview
The bromodomain of CREB-binding protein (CBP) is a protein module that recognizes and binds to acetylated lysine residues on histones and other proteins. This interaction facilitates chromatin remodeling and transcriptional activation. It is a therapeutic target for diseases involving epigenetic dysregulation.
- Other names
- CBP BromodomainCREBBP Bromodomain
02
Mechanism of action
Inhibition of bromodomain-acetylated lysine interaction
03
Biological functions
Chromatin remodelingTranscriptional coactivationEpigenetic regulation
04
Disease associations
CancerMetabolic disordersNeurological disorders
05
Interacting drugs
IACS‑70654
2 more in the full profile.
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