Target intelligence / Profile preview

CREB-binding Protein Bromodomain

Molecular classification
Bromodomain, Epigenetic regulator, Histone modification reader
01

Overview

The bromodomain of CREB-binding protein (CBP) is a protein module that recognizes and binds to acetylated lysine residues on histones and other proteins. This interaction facilitates chromatin remodeling and transcriptional activation. It is a therapeutic target for diseases involving epigenetic dysregulation.

Other names
CBP BromodomainCREBBP Bromodomain
02

Mechanism of action

Inhibition of bromodomain-acetylated lysine interaction

03

Biological functions

Chromatin remodelingTranscriptional coactivationEpigenetic regulation
04

Disease associations

CancerMetabolic disordersNeurological disorders
05

Interacting drugs

IACS‑70654

2 more in the full profile.

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