CRIPTO pseudogene 2 (CRIPTOP2)

CRIPTO pseudogene 2 (CRIPTOP2) is a processed pseudogene in the human genome[4]. Pseudogenes are defective copies of protein-coding genes, often produced by retrotransposition, and typically lack the regulatory elements or sequence integrity necessary to produce a functional protein[2]. While some pseudogenes can regulate gene expression through complex RNA-mediated mechanisms (such as acting as miRNA decoys), most—including CRIPTOP2—are functionally inert and are not studied as therapeutic targets or biological receptors[2][4]. The parental gene, CRIPTO (TDGF1), is a growth factor involved in embryonic development and cancer, but CRIPTOP2 itself does not play an analogous role[4][2].\n\nIf you need information on the canonical, protein-coding CRIPTO (TDGF1, known as Teratocarcinoma-derived growth factor 1), please specify, as CRIPTOP2 and CRIPTO are distinct entities[4].

Other names

CR-2CRIPTO-2CRIPTOP2