Target intelligence / Profile preview

CTAGE family member 6 (CTAGE6)

Target
CTAGE6
Molecular classification
Other (not classified as receptor, transporter, enzyme, ion channel, transcription factor, or histone modifier)
01

Overview

CTAGE family member 6 (CTAGE6), also known as “protein cTAGE-6” or via its pseudogene annotation CTAGE6P, is a predicted protein-coding gene associated with ER-to-Golgi vesicle transport and protein secretion[2]. Its protein product is predicted to be membrane-associated, located at endoplasmic reticulum exit sites and the ER membrane. There is no evidence that CTAGE6 has been leveraged as a target for therapeutic intervention, nor is it classified under major families such as receptors, enzymes, transporters, or transcription factors. Disease associations (Waisman Syndrome, hereditary keratitis) are found in annotation databases but lack strong mechanistic or clinical support. The gene remains poorly characterized, with limited information on biological roles and no validated drug interactions or functional biomarkers[2].

Other names
CTAGE family member 6CTAGE6CTAGE6PProtein cTAGE-6MGC41943Cutaneous T-cell lymphoma-associated antigen 6Putative protein cTAGE-6
02

Mechanism of action

Not applicable; no drugs targeting CTAGE6 are reported.

03

Biological functions

Endoplasmic reticulum to Golgi vesicle-mediated transportProtein secretionVesicle cargo loading
04

Disease associations

Waisman SyndromeHereditary Keratitis

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