Target intelligence / Profile preview

cTAGE family member 8 (CTAGE8)

Target
CTAGE8
Molecular classification
Other (predicted membrane-associated, not a classical receptor, enzyme, transporter, or transcription factor)
01

Overview

cTAGE family member 8 (CTAGE8) is a protein-coding gene predicted to function in cargo loading and protein secretion in the endoplasmic reticulum–Golgi transport pathway[1][5][6]. It is annotated as a membrane-associated protein, active predominantly at the endoplasmic reticulum exit site and membrane[1]. CTAGE8’s human protein existence is only supported at the transcript level[4], and it has been identified as a paralog of CTAGE4[1]. There is no evidence to suggest a direct role in disease, interaction with drugs, use as a biomarker, or involvement in classical therapeutic targets such as receptors, enzymes, or transporters[1][5][6]. While occasionally referenced as "cutaneous T-cell lymphoma-associated antigen 8" in generic alias listings, there is no scientific evidence supporting any direct role in lymphoma, cancer, or other diseases[1][5][6]. CTAGE8 should not be considered a therapeutic target.

Other names
cTAGE family member 8CTAGE8Protein cTAGE-8CTAGE4cTAGE family member 4 pseudogeneCutaneous T-cell lymphoma-associated antigen 8Protein cTAGE-4cTAGE family member 4
02

Mechanism of action

Not applicable; no drugs known to target this protein

03

Biological functions

Endoplasmic reticulum to Golgi vesicle-mediated transportProtein secretionVesicle cargo loading
04

Disease associations

None established; no direct disease association reported in public sources
05

Safety considerations

None reported; no therapeutic context or druggability
06

Interacting drugs

None reported or associated
07

Biomarkers

None reported

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