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Cullin 2 pseudogene is a non-functional genomic DNA sequence that resembles the protein-coding gene for cullin 2, but does not produce a functional protein product. Pseudogenes arise naturally via gene duplication or retrotransposition followed by loss-of-function mutations and are generally considered genomic 'dead ends' without active roles in cellular processes or disease[1][3]. Accordingly, the cullin 2 pseudogene is not considered a therapeutic target and has no direct involvement in drug mechanisms, disease biology, or biomarker applications[1][2][3][4].
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