Cutaneous T-cell lymphoma-associated antigen 1 pseudogene (CTAGE1 pseudogene)

Cutaneous T-cell lymphoma-associated antigen 1 pseudogene (ENSG00000274549) is a non-coding genomic segment located in the human genome. It is related by sequence homology to the CTAGE1 gene, which encodes a tumor-associated antigen expressed in cutaneous T-cell lymphoma and certain other malignancies. However, as a pseudogene, ENSG00000274549 does not encode a functional protein, and there is no direct evidence for it serving a regulatory or pathological role. Pseudogenes are generally regarded as nonfunctional remnants of genes that have accumulated mutations preventing protein expression, though some pseudogenes can modulate gene expression at the RNA level in rare cases. This specific pseudogene is not regarded as a therapeutic target, nor is it directly implicated in disease biology or used as a biomarker. ENSG00000274549, the "cutaneous T-cell lymphoma-associated antigen 1 pseudogene," is a nonfunctional pseudogene and should not be considered a therapeutic target. It is properly classified as a pseudogene, with no established protein expression, therapeutic relevance, or associated drugs. If you are seeking information on a druggable cancer target, you likely wish to refer to the closely related protein-coding gene CTAGE1.

Other names

CTAGE1 pseudogeneCutaneous T-cell lymphoma-associated antigen 1 pseudogene