Target intelligence / Profile preview

Skin Vasculature

Molecular classification
Vascular Network, Tissue
01

Overview

The skin vasculature is the network of blood vessels within the skin, primarily located in the dermis and subcutaneous layers. It is essential for delivering nutrients and oxygen, removing waste products, regulating body temperature, supporting immune responses, and maintaining overall skin health. It comprises superficial, deep, and subcutaneous plexuses, and its function is regulated by neural, hormonal, and endothelial signaling.

Other names
Cutaneous VasculatureDermal Blood VesselsSkin Blood Supply
02

Mechanism of action

Varies depending on the specific drug, including vasodilation, vasoconstriction, inhibition of inflammation, and inhibition of angiogenesis.

03

Biological functions

Nutrient DeliveryOxygen SupplyWaste RemovalThermoregulationImmune ResponseWound Healing
04

Disease associations

Inflammatory DiseasesVascular MalformationsSystemic Diseases with Cutaneous InvolvementTumor Angiogenesis
05

Safety considerations

Impaired wound healingEdemaIschemiaHypertensionHypotension
06

Interacting drugs

Vasodilators

3 more in the full profile.

07

Biomarkers

Vascular densityEndothelial cell markers (e.g., CD31)Angiogenic factors (e.g., VEGF)Inflammatory markers

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