Molecular Classification
Bacterial Antigen, Bacterial Component
Other Names
Propionibacterium acnes Antigen, C. acnes Molecular Components, P. acnes Antigen
Disease Roles
Acne vulgarisPeriprosthetic joint infectionEndocarditis

Cutibacterium acnes Antigen Overview

Cutibacterium acnes antigen refers to molecular components derived from C. acnes that are recognized by the host immune system. These antigens can be detected in clinical samples and are associated with host inflammatory responses during infection or colonization. While typically non-pathogenic, C. acnes can act as an opportunistic pathogen implicated in various infections and inflammatory conditions, and its antigens can be used diagnostically.

Mechanism of Action

N/A

Biological Functions

Immune response activation
Inflammation induction
Microbial colonization
Immunomodulation

Disease Associations

Acne vulgaris
Periprosthetic joint infection
Endocarditis
Osteomyelitis
Sarcoidosis
Implant-associated infections

Safety Considerations

  • False positive in diagnostic assays
  • Overestimation of infection severity

Associated Biomarkers

Biomarker
Elevated levels in synovial fluid (e.g., in periprosthetic joint infection)
Correlation with local inflammation