Cyclic AMP Pathway (None)

The cyclic AMP (cAMP) pathway is a fundamental intracellular signaling cascade that transduces extracellular signals into diverse cellular responses. cAMP acts as a second messenger, relaying signals from cell surface receptors to intracellular targets and regulating numerous physiological processes including metabolism, gene transcription, cell growth, and differentiation. Key components include Adenylyl Cyclase, G Protein-Coupled Receptors, Phosphodiesterases, Protein Kinase A, and EPAC. Dysregulation of the cyclic AMP pathway is implicated in various diseases including endocrine disorders, cardiovascular disease, neurological conditions, and cancer. Key drug targets within this pathway include GPCRs, Phosphodiesterases, and Protein Kinase A.

Modulation of cAMP levels, PKA activity, and downstream signaling cascades