Target intelligence / Profile preview

Cyclin B2 (CCNB2)

Target: CCNB2
Molecular classification: Cyclin, Protein Kinase

Overview

Cyclin B2 is a key regulatory protein involved in cell cycle control, particularly at the G2/M transition. It forms complexes with CDK1 (p34cdc2) and regulates entry into mitosis. Overexpression is implicated in various cancers, making it a potential therapeutic target.

Other names: Cyclin B2

Biological functions

Cell cycleRegulation of G2/M transitionMitotic arrest

Disease associations

Cancer

Biomarkers

Prognostic marker in cancer

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