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Target intelligence / Profile preview
Cyclin-dependent kinase 17 (CDK17)
- Target
- CDK17
- Molecular classification
- Enzyme, Ser/Thr protein kinase, Cyclin-dependent kinase
01
Overview
CDK17 is a serine/threonine protein kinase and a member of the cyclin-dependent kinase family. It is predicted to be involved in the regulation of cell cycle phase transition and may play a role in terminally differentiated neurons. CircCDK17, a circular RNA derived from the CDK17 gene, has been implicated in promoting proliferation and metastasis of ovarian and cervical cancer cells.
- Other names
- PCTAIRE2PCTK2Serine/threonine-protein kinase PCTAIRE-2
02
Biological functions
Phosphorylates histone H1Cell cycle regulationNeuron differentiation (possible)
03
Disease associations
Cancer
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