Drug pipeline
Explore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
Cyclin-dependent kinase 3
- Molecular classification
- Enzyme, Protein kinase, Serine/threonine-protein kinase, Cyclin-dependent kinase
01
Overview
Cyclin-dependent kinase 3 (CDK3) is a serine/threonine protein kinase that plays a role in cell cycle control, particularly at the G0-G1 and G1-S transitions. It requires interaction with cyclins for activation and can phosphorylate histone H1. Recent studies suggest it may have oncogenic properties and be involved in cancer progression. While it's a potential therapeutic target, current inhibitors primarily focus on other CDK family members.
- Other names
- CDK3Cell division protein kinase 3
02
Mechanism of action
CDK3 inhibitors (not specific, as most target other CDKs like 2/4/6/7/9)
03
Biological functions
Cell cycle regulationG0-G1 transitionG1-S transitionHistone H1 phosphorylation
04
Disease associations
CancerEsophageal squamous cell carcinomaLung cancerSkin cancer
05
Safety considerations
Potential for off-target effects due to sequence similarity with other CDKsInhibition of essential cell cycle processes
Beyond the preview
Go deeper on Cyclin-dependent kinase 3.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Follow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Compare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Investigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Explore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Connect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Cyclin-dependent kinase 3.