Cyclin dependent kinase 5 pseudogene 1 (CDK5P1)

Cyclin dependent kinase 5 pseudogene 1 (CDK5P1) is a pseudogene, meaning it is a non-protein-coding segment of DNA that resembles a functional gene (CDK5) but does not produce an active enzyme or functional product. It does not have a known biological or therapeutic function, nor is it implicated in disease pathways, biomarker panels, or targeted by drugs. CDK5P1 is explicitly annotated as a "pseudogene" in authoritative gene databases. Pseudogenes are DNA sequences related to functional genes but typically lack the ability to code for functional proteins due to mutations or disruptions in their sequences. Thus, CDK5P1 is not a functional enzyme, receptor, transporter, or any active molecular target. As such, it is not relevant for drug targeting, disease involvement, or biomarker use. The gene for which it is named, CDK5, is functional and important in neurology and cell biology, but CDK5P1 itself is not an active biological entity. CDK5P1 does not encode protein and does not perform biological functions on its own. Listings such as GeneCards make it clear it is a pseudogene, with no protein or clinical annotations. If the intention was to refer to the functional kinase, that would be "cyclin-dependent kinase 5 (CDK5)". Cyclin-dependent kinase 5 (CDK5) is a protein-coding gene and a serine/threonine kinase involved in neuronal development, function, and disease, but CDK5P1 is not the same as CDK5. CDK5 is a known therapeutic target involved in neurodegenerative diseases, cell differentiation, apoptosis, and more. Drugs and research targeting CDK5 (not CDK5P1) exist. In summary, CDK5P1 is a pseudogene with no direct biological, therapeutic, or clinical function. Its inclusion as a molecular target is incorrect. If therapeutic or biological information is required, it should be for the protein-coding gene cyclin-dependent kinase 5 (CDK5), not CDK5P1.

Other names

CDK5PScyclin-dependent kinase 5 pseudogeneCDK5P1