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Target intelligence / Profile preview
Cyclin-L2 (CCNL2)
- Target
- CCNL2
- Molecular classification
- Cyclin family protein, Transcriptional regulator
01
Overview
Cyclin-L2 is a member of the cyclin family whose protein product interacts with multiple factors, including RNA polymerase II, splicing proteins, and cyclin-dependent kinases. It functions in regulating pre-mRNA splicing and may induce apoptosis by modulating the transcription and RNA processing of apoptosis-related genes. The gene has multiple alternatively spliced transcript variants leading to different isoforms. CCNL2 is associated with some cancers, such as retinal and ocular cancer, but is not recognized as a direct therapeutic drug target or receptor[1][2][3][4][6].
- Other names
- Cyclin-L2CCNL2SB138ania-6bPCEEHLA-ISOCCNSPaneth cell-enhanced expression proteincyclin SANIA-6BCCNMcyclin M
02
Biological functions
Pre-mRNA splicingApoptosis inductionCell cycle regulationTranscriptional control
03
Disease associations
Cancer (Retinal cancer, Ocular cancer)
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