Cysteinyl-tRNA synthetase 1 pseudogene 1 (CARS1P1)

Cysteinyl-tRNA synthetase 1 pseudogene 1 (CARS1P1) is a processed pseudogene, meaning it is a non-functional genomic copy of the parental CARS1 (“cysteinyl-tRNA synthetase 1”) gene and does not encode an active enzyme or protein product. Pseudogenes like CARS1P1 often arise by retrotransposition and lack introns and regulatory elements that would enable protein expression, thus they usually do not have molecular function or therapeutic target potential. Their sequence similarity to functional genes can complicate genetic analysis and diagnostics but does not imply functional protein production or druggability. CARS1P1 is not considered a therapeutic target, as it is not a protein, receptor, enzyme, or functional RNA. This entry is best classified as a processed pseudogene, a genomic relic of the functional CARS1 gene, which encodes cysteinyl-tRNA synthetase—an enzyme critical in protein synthesis; however, CARS1P1 itself is not functional. There is nothing to support a role as a biomarker, drug target, or in pathogenesis.

Other names

CARSP1