Cystic fibrosis transmembrane conductance regulator pseudogene 3 (CFTRP3)

Cystic fibrosis transmembrane conductance regulator pseudogene 3 (CFTRP3) is a genomic DNA sequence that is highly homologous to portions of the protein-coding *CFTR* gene but contains disabling mutations (such as frameshifts, truncations, or lack of regulatory elements) that prevent it from producing a functional protein. CFTRP3 is thus classified as a **pseudogene**; it does not contribute to the chloride channel or transporter activity characteristic of the canonical CFTR protein, nor is it involved in cystic fibrosis or any other disease. Its sequence is used in genomic analysis and evolutionary studies but does not have clinical, pharmacological, or diagnostic utility.

Other names

CFTR pseudogene 3CFTRP3Cystic fibrosis transmembrane conductance regulator pseudogene 3