Target intelligence / Profile preview

Cytochrome c, somatic pseudogene 51 (CYCSP51)

Target
CYCSP51
Molecular classification
Pseudogene, Other
01

Overview

**CYCS pseudogene 51 (CYCSP51)** is a full-length human pseudogene derived from the cytochrome c gene, also known as HCP1. It does not produce a functional protein but serves as an inactive genetic vestige resulting from retrotransposition events during evolution. There is no evidence it acts as a receptor, enzyme, transporter, or has a therapeutic function. This pseudogene is not considered a molecular target and does not participate in cellular signaling, biological pathways, or disease mechanisms[6][7]. Its identification is of evolutionary and genomic interest only. **Key information:** - CYCSP51 is classified strictly as a pseudogene in humans and has no active or actionable biological function[6][5][7]. - The label "HCP1" here refers to human cytochrome c pseudogene 1 and should not be confused with Hcp1 from bacterial Type VI Secretion System studies[1][3], which is a protein with structural and immunological relevance in bacterial pathogenesis. **Notable clarification:** - There is no evidence CYCSP51/HCP1 is a molecular target (drug, receptor, enzyme, etc.) in humans. - If the intent is to describe the bacterial Hcp1 protein relevant to secretion systems, that is a completely different molecule and context[1][3]. - CYCSP51 does not meet criteria for inclusion as a receptor, enzyme, transporter, or any other conventional therapeutic target; it is only a pseudogene.

Other names
CYCS pseudogene 51cytochrome c, somatic pseudogene 51HCP1human cytochrome c pseudogene 1
02

Mechanism of action

None (not a target for therapeutic intervention; does not possess an actionable mechanism)

03

Biological functions

None (does not encode a functional protein; no active biological function)
04

Disease associations

None (no evidence or established links to diseases; serves as a molecular relic or marker only)
05

Safety considerations

None (as a non-functional pseudogene, there are no safety concerns or challenges relevant to drug development)
06

Interacting drugs

None (no small molecules, biologics, or approved drugs interact with this pseudogene)
07

Biomarkers

None (not used for patient selection or efficacy monitoring)

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