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Cytochrome c oxidase assembly factor 5 pseudogene
- Molecular classification
- Other
01
Overview
Cytochrome c oxidase assembly factor 5 pseudogene (ENSG00000282852) is a non-functional copied sequence of the protein-coding gene COA5, which encodes a mitochondrial protein essential for the assembly of complex IV (cytochrome c oxidase) of the respiratory chain. The pseudogene does not produce a functional protein and has no described biological activity or clinical significance as a target. The functional counterpart, COA5 (cytochrome c oxidase assembly factor 5), is critical for mitochondrial function, and mutations in COA5 can cause mitochondrial complex IV deficiency with severe clinical outcomes. However, the pseudogene itself has no proven involvement in drug interaction, disease, or therapeutic modulation.
- Other names
- COA5 pseudogeneCytochrome c oxidase assembly factor 5 pseudogeneC2orf64 pseudogene (by analogy to COA5/C2orf64 gene aliases)
02
Biological functions
Other
03
Disease associations
Other
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