Cytochrome c oxidase subunit 1 pseudogene

A Cytochrome c oxidase subunit 1 pseudogene is a segment of nuclear DNA that closely resembles the functional gene encoding mitochondrial cytochrome c oxidase subunit 1, but it does not encode a functional protein product. Pseudogenes like this one may arise from gene duplication or retrotransposition events and are typically non-functional. They do not have a recognized therapeutic or physiological role and are not considered druggable targets. In molecular research, they can be used as markers of evolution or gene regulation but are not involved in active metabolism, signaling, or disease pathogenesis as their functional gene counterpart is[5][8]. If you were seeking information on the functional enzyme (cytochrome c oxidase subunit 1, abbreviated as COX1 or MT-CO1), note that is a key mitochondrial enzyme essential for oxidative phosphorylation, widely used in species identification (DNA barcoding) and associated with mitochondrial diseases, but the pseudogene discussed here is unrelated to those functions[5][8]. Summary: This entry refers to a pseudogene, which is not considered a functional or therapeutic target. If you require information about the active enzyme, refer to "Cytochrome c oxidase subunit 1" (without "pseudogene"), and not this non-coding genomic element.

Other names

MT-CO1 pseudogeneCOX1 pseudogene