Cytochrome c oxidase subunit 5B pseudogene 6 (COX5BP6)

Cytochrome c oxidase subunit 5B pseudogene 6 (COX5BP6) is a human pseudogene that shares sequence similarity with protein-coding genes in the cytochrome c oxidase (COX) family. Pseudogenes like COX5BP6 are generally considered nonfunctional due to mutations that prevent their translation into functional proteins[2][3]. While some pseudogenes are transcribed and may regulate their ancestral genes via noncoding RNA mechanisms (such as acting as microRNA decoys), there are no specific publications or data supporting regulatory functions or disease relevance for COX5BP6 specifically[2][3]. It is not referenced as a therapeutic target, drug-interacting gene, or biomarker.\n\n*General context on pseudogenes:*\nAlthough pseudogenes can have regulatory functions at the RNA level for their parental genes—sometimes influencing cancer and other disease pathways via competing endogenous RNA networks or serving as miRNA decoys—such effects require specific evidence for each pseudogene[2][3]. There is currently no evidence that COX5BP6 functions in this manner.